I have a tangent perspective that relates to the rat addictions. You mention the difficulty of finding a control group. One of my favorite words is "useful." If we individuate (or tribalize?) wildness relationship, and question what the human needs from wilderness, the answer is "survival": aka "persistence." Over the billions of years of animal evolution, the thing that allows multigenerational persistence is a real usefulness to one's own future. This means a deep connection to where and how the next meal and sanctuary is under one's own control. Everything about domestication displaces this control via multiple monetized pathways. We spend our lives seeking to reestablish that control (hoarding, scrolling, eating, etc). So, yes, I think you are touching a very important point with zoochosis, and it's much more than having greenspace to get fresh air and dollarized exercise. Competitive domestication is making people insane and the systemic answer is "more competition" and "more resource extraction for more mindless jobs." Sounds wild, doesn't it?